Cellulose Derivatives

Our Cellulose Derivatives are top of the class with excellent product characteristics for a broad range of applications.

Our MCC and sMCC combines low black spot level with excellent flow and compaction properties during processing.

The perfect match for solid and semi-fluid dosage forms.

All our MCC types are spray dried only with significant cost savings and process advantages in all applications.

Technical

Micro Crystalline Cellulose (MCC) 101, technical
Micro Crystalline Cellulose (MCC) 102, technical

Food

Micro Crystalline Cellulose (MCC) 101, E460i, FCC
Micro Crystalline Cellulose (MCC) 102, E460i, FCC

Pharmaceutical

USP/Ph.Eur/JP/BP/IP

Micro Crystalline Cellulose (MCC) 101
Micro Crystalline Cellulose (MCC) 102
Micro Crystalline Cellulose (MCC) 112
Micro Crystalline Cellulose (MCC) 200
Micro Crystalline Cellulose (MCC) 301
Micro Crystalline Cellulose (MCC) 302
silicified Micro Crystalline Cellulose (sMCC) 50
silicified Micro Crystalline Cellulose (sMCC) 90
silicified Micro Crystalline Cellulose (sMCC) 90 HD
Powder Cellulose (PC)
Micro Crystalline Cellulose Gel (RC Type)

USE CASE: Spray Dried MCC Vs Bulk Dried MCC in the Tabletting Process

IN PROCESS PARAMETER

Flowability
Porosity
Control on PSD
Segregation tendency
Cohesivity

SPRAY DRIED MCC

Higher
Higher
Superior
Lesser
Lesser

BULK DRIED MCC

Less
Less
Inferior
Higher
Higher

TABLETTING PROPERTIES

Compressibility/Hardness
Compaction forces
Disintegration Time
Weight Variation
Suitable for High Speed Tabletten
Dwell Time Impact
Production Output
Machine Wear and Tear

SPRAY DRIED MCC

Higher
Lower
Faster
Low
More Suitable
Less Impact
Higher
Less due to lower compaction forces

BULK DRIED MCC

Lower
Higher
Slower
High
Less Suitable
More Impact
Lesser
Higher on the long run

Economics

Overall Costs
R&D Savings
Purchasing Costs
Maintenance Costs
Addition Cost for WG instead of DC

SPRAY DRIED MCC

Lower
Significant
Higher
Low
Less properly

BULK DRIED MCC

Higher
Low
Lower
High
Properly

Available Products by Application (TABLETTING)

Application

WET GRANULATION

DIRECT COMPRESION

HIGH DENSITY

LOW MOISTURE

Product Grades

PH 101

PH 102
PH 200
SMCC 50
SMCC 90

PH 301
PH 302
SMCC 90 HD

PH 102 LM
PH 103
PH 112
PH 200 LM

PSD (microns)

100
170
50
125

50
100
125

100
50
100
170

LOD (%)

NMT 6.0

NMT 6.0
NMT 6.0
NMT 6.0
NMT 6.0

NMT 6.0
NMT 6.0
NMT 6.0

NMT 3.0
NMT 3.0
NMT 2.0
NMT 3.0

Bulk Density (g/ml)

0.26 – 0.33

0.26 – 0.33
0.28 – 0.36
0.25 – 0.37
0.25 – 0.37

0.34 – 0.45
0.35 – 0.46
0.38 – 0.50

0.26 – 0.33
0.26 – 0.33
0.26 – 0.33
0.28 – 0.36

Available Products by Application (Capsule Filling)

Application

STANDARD & HIGH SPEED FILLING

Product Grades

PH 102
PH 200

PSD (microns)

100
170

LOD (%)

NMT 6.0
NMT 6.0

Bulk Density (g/ml)

0.26 – 0.33
0.28 – 0.36